| Characteristics | |||||||
| Molecular Formula | C₃₈H₄₉N₉O₅ | ||||||
| CAS Number | 170851-70-4 | ||||||
| Molar Mass | 711.853 g/mol | ||||||
| Amino Acid Sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH₂ | ||||||
| Synonyms | NNC 26-0161, Ipam, Ipamorelin Acetate | ||||||
| Solubilit | Water-soluble (soluble in sterile saline) | ||||||
| rganoleptic Profile | White to off-white lyophilized powder | ||||||
| Composition | Lyophilized powder—requires reconstitution | ||||||
Product Introduction:
Ipamorelin is a synthetic growth hormone secretagogue (GHS) peptide designed to stimulate the natural release of growth hormone (GH) in the body. This highly selective, water-soluble peptide has been extensively researched for its potential to support lean muscle growth, fat loss, and overall metabolic health. Ipamorelin has shown promise in promoting muscle recovery, enhancing sleep quality, and improving skin and bone health. It may also have anti-aging and anti-inflammatory properties. Ipamorelin has been studied for its potential to aid in fitness performance, body composition improvement, and general wellness support. Requires reconstitution before use.
- How does Ipamorelin work?
Ipamorelin exerts its effects through several interconnected mechanisms:
GH Secretagogue Receptor Activation: Ipamorelin binds to and activates growth hormone secretagogue receptors (GHSR-1a), which are highly expressed in the pituitary gland and hypothalamus. This activation triggers a signaling cascade that stimulates the natural, pulsatile release of growth hormone (GH) from the anterior pituitary.
Pituitary Effects: In pituitary somatotroph cells, ipamorelin enhances GH secretion by increasing intracellular calcium levels and activating cyclic AMP (cAMP) pathways, without disrupting the body’s natural GH rhythm.
Central Nervous System Effects: Ipamorelin acts on GHSR-1a receptors in the hypothalamus to regulate GH release, with minimal impact on other pituitary hormones like prolactin, cortisol, or thyroid-stimulating hormone (TSH), ensuring high selectivity.
- Research
GH & IGF-1 Regulation: Ipamorelin selectively stimulates GH secretion, which in turn elevates insulin-like growth factor 1 (IGF-1) levels, supporting anabolic processes in muscle, bone, and connective tissue.
Body Composition & Metabolism: Research demonstrates that ipamorelin promotes lean muscle mass growth, enhances fat metabolism, and supports healthy body composition in clinical studies.
Recovery & Wellness: Ipamorelin has been studied for its potential to accelerate muscle recovery, improve sleep quality, and support overall metabolic health and anti-aging processes.
Cardiometabolic Effects: Research indicates ipamorelin may support healthy lipid profiles, blood sugar regulation, and cardiovascular wellness through its GH-mediated metabolic benefits.
- Side Effects
The most common side effects associated with Ipamorelin include:
• Headache
• Flushing
• Dizziness
• Nausea
• Fatigue
- Summary
Ipamorelin represents a significant advancement in growth hormone secretagogue research, offering a highly selective tool for investigating the multifaceted roles of GH signaling in muscle growth, metabolism, and wellness. Its demonstrated efficacy in stimulating natural GH release, improving body composition, and supporting recovery makes it a valuable subject for ongoing research in fitness performance, anti-aging, and metabolic health. As investigations continue, ipamorelin may provide insights into novel therapeutic strategies for addressing age-related muscle loss, metabolic disorders, and overall wellness optimization.
- Resource
All products on this site are for research and development use only. Products are not for human consumption of any kind. The statements made on this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure, or prevent any disease. Power Peptides is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Power Peptides is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act. All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption. Power Peptides Products are intended strictly for research purposes only. These products are not approved by the U.S. Food and Drug Administration (FDA) for human consumption or medical use. Under no circumstances should these peptides be used for any purpose other than research. By purchasing or using our peptides, you acknowledge and agree that you will use them solely in accordance with applicable laws and regulations and that you accept full responsibility for their use. Statements made on this website have not been evaluated by the USA Food and Drug Administration.











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