| Characteristics | |||||||
| Molecular Formula | C50H69N15O9 | ||||||
| CAS Number | 121062-08-6 | ||||||
| Molar Mass | 1025.2 g/mol | ||||||
| Amino Acid Sequence | Ac-Ser-Ty-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 | ||||||
| Synonyms | MT-2, Melanotan II, Melanotan-2 Acetate | ||||||
| Solubilit | Soluble in Water | ||||||
| rganoleptic Profile | White powder | ||||||
| Composition | Lyophilized powder – requires reconstitution | ||||||
Product Introduction:
MT-2 is a synthetic peptide analog of the naturally occurring alpha-melanocyte-stimulating hormone (α-MSH). This stable, water-soluble peptide has been extensively researched for its potential to stimulate melanin production in the skin, resulting in a natural, long-lasting tan without prolonged UV exposure. MT-2 has shown promise in promoting skin pigmentation, reducing sun sensitivity, and supporting libido enhancement. It may also have appetite-suppressing and fat-burning properties. MT-2 has been studied for its potential to aid in tanning for individuals with fair skin, photosensitivity disorders, and those seeking a sunless tan. Requires reconstitution before use.
- How does Melanotan 2 (MT-2)work?
Melanotan 2 (MT-2) exerts its effects through multiple interconnected mechanisms:
MC Receptor Activation: MT-2 binds to and activates melanocortin receptors (primarily MC1-R, MC3-R, MC4-R), which are expressed in various tissues including melanocytes, the central nervous system, and adipose tissue. This activation initiates intracellular signaling cascades, primarily through cyclic AMP (cAMP) pathways.
Melanogenic Effects: In skin melanocytes, MT-2 enhances melanin production by upregulating tyrosinase activity, contributing to accelerated skin tanning and UV protection.
Central Nervous System Effects: MT-2 crosses the blood-brain barrier and acts on MC3/4-R receptors in the hypothalamus. This central action regulates appetite, energy metabolism, and sexual function.
- Research
Pigmentation & Tanning: MT-2 stimulates melanin synthesis in melanocytes, promoting a natural, uniform tan with reduced UV exposure, and has been studied for photosensitivity disorders like erythropoietic protoporphyria.
Appetite & Weight Regulation: By acting on central melanocortin receptors, MT-2 reduces food intake and increases energy expenditure, showing potential for weight management in clinical studies.
Sexual Function: Research indicates MT-2 may enhance libido and sexual arousal in both men and women, with demonstrated efficacy in treating erectile dysfunction.
Metabolic Effects: Studies suggest MT-2 may improve insulin sensitivity and lipid profiles, supporting metabolic health in preclinical models.
- Side Effects
The most common side effects associated with MT-2 include:
– Nausea
– Flushing
– Increased libido
– Loss of appetite
– Headache
– Darkening of moles/freckles
– Facial flushing
- Summary
Melanotan 2 (MT-2) represents a significant advancement in melanocortin receptor agonist research, offering a potent tool for investigating the multifaceted roles of melanocortin signaling in skin pigmentation, metabolic regulation, and sexual function. Its demonstrated efficacy in tanning, appetite suppression, and libido enhancement makes it a valuable subject for ongoing research in cosmetic dermatology, obesity, and sexual health disorders. As investigations continue, MT-2 may provide insights into novel therapeutic strategies for addressing photosensitivity, metabolic syndrome, and sexual dysfunction.
- Resource
All products on this site are for research and development use only. Products are not for human consumption of any kind. The statements made on this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure, or prevent any disease. Power Peptides is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Power Peptides is not our outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act. All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption. Power Peptides Products are intended strictly for research purposes only. These products are not approved by the U.S. Food and Drug Administration (FDA) for human consumption or medical use. Under no circumstances should these peptides be used for any purpose other than research. By purchasing or using our peptides, you acknowledge and agree that you will use them solely in accordance with applicable laws and regulations and that you accept full responsibility for their use. Statements made on this website have not been evaluated by the USA Food and Drug Administration.










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