| Characteristics | |||||||
| Molecular Formula | C₂₁₂H₃₅₀N₅₆O₇₈S | ||||||
| CAS Number | 77591-33-4 | ||||||
| Molar Mass | 4963.44 g/mol | ||||||
| Amino Acid Sequence | Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES | ||||||
| Synonyms | TB-500, Thymosin Beta-4, Tβ4, Thymosin β4, TB500 | ||||||
| Solubilit | Soluble in Water | ||||||
| rganoleptic Profile | White to off-white lyophilized powder | ||||||
| Composition | Lyophilized powder – requires reconstitution | ||||||
Product Introduction:
TB-500 is a synthetic peptide derived from the naturally occurring thymosin beta-4 protein, a key regulator of cell migration and tissue repair. This highly stable, water-soluble peptide has been extensively researched for its powerful potential to accelerate healing across multiple tissue types, including muscles, tendons, ligaments, and skin. TB-500 has shown remarkable promise in promoting angiogenesis, reducing inflammation, and supporting full tissue regeneration. It may also exhibit neuroprotective, anti-fibrotic, and wound-healing properties that support overall tissue health. TB-500 has been studied for its potential to aid in the recovery of conditions such as muscle strains, tendon injuries, joint damage, and chronic skin wounds. Requires reconstitution before use.
- How does TB-500 work?
TB-500 exerts its effects through multiple interconnected cellular mechanisms:
Actin Regulation & Cell Migration: TB-500 binds to actin monomers, regulating actin cytoskeleton dynamics to promote cell migration, a core process in tissue repair and regeneration.
Angiogenesis Promotion: TB-500 stimulates the formation of new blood vessels, enhancing blood flow to injured tissues and accelerating wound healing.
Anti-Inflammatory & Anti-Fibrotic Action: TB-500 modulates inflammatory cytokine release, reduces excessive inflammation at injury sites, and inhibits scar tissue formation (fibrosis) to support functional tissue recovery.
Tissue Repair Signaling: TB-500 activates key signaling pathways involved in cell proliferation and differentiation, supporting the regeneration of muscles, tendons, ligaments, and skin.
- Research
Musculoskeletal Recovery: Extensive research demonstrates TB-500’s ability to accelerate healing of muscle strains, tendon tears, ligament injuries, and joint damage, reducing recovery time for soft tissue trauma.
Wound Healing & Skin Regeneration: Studies show TB-500 promotes rapid closure of acute and chronic skin wounds, reduces scarring, and supports skin tissue regeneration.
Cardiovascular & Tissue Protection: Research indicates TB-500 supports cardiac tissue repair after injury, protects endothelial function, and may have benefits in reducing tissue damage from ischemia.
Neuroprotective Effects: Preclinical studies suggest TB-500 supports neural cell migration and repair, with potential applications in central nervous system injury recovery.
- Side Effects
The most common side effects associated with TB-500 include:
– Mild fatigue
– Headache
– Temporary redness or irritation at injection site
– Mild gastrointestinal discomfort (rare)
– Transient muscle soreness during initial recovery phase
- Summary
TB-500 represents a pivotal advancement in tissue repair peptide research, offering a powerful tool for investigating the molecular mechanisms of soft tissue regeneration, wound healing, and inflammation modulation. Its demonstrated efficacy in accelerating musculoskeletal recovery, reducing scarring, and supporting vascular health makes it a valuable subject for ongoing research in sports medicine, wound care, and regenerative biology. As investigations continue, TB-500 may provide critical insights into novel therapeutic strategies for addressing a wide range of tissue injury and repair challenges.
- Resource
All products on this site are for research and development use only. Products are not for human consumption of any kind. The statements made on this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure, or prevent any disease. Power Peptides is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Power Peptides is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act. All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption. Power Peptides Products are intended strictly for research purposes only. These products are not approved by the U.S. Food and Drug Administration (FDA) for human consumption or medical use. Under no circumstances should these peptides be used for any purpose other than research. By purchasing or using our peptides, you acknowledge and agree that you will use them solely in accordance with applicable laws and regulations and that you accept full responsibility for their use. Statements made on this website have not been evaluated by the USA Food and Drug Administration.













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